Reference no: EM133916686
Assignment: Case Studies
Case studies are a useful way for you to apply your knowledge of pharmacokinetics and pharmacodynamic aspects of pharmacology to specific patient cases and health histories.
For this Assignment, you evaluate drug treatment plans for patients with various disorders and justify drug therapy plans based on patient history and diagnosis.
To Prepare:
Review the case study posted in "Announcements" by your Instructor for this Assignment
Review the information provided and answer questions posed in the case study
When recommending a medication, write out a complete prescription for the medication
Whenever possible, use clinical practice guidelines in developing your answers when possible
Include at least three references to support your answer and cite them in APA format. Get expert-level assignment help in any subject.
Cardiovascular System
In Week 2, we will continue our pharmacology journey and apply the concepts to the cardiovascular system. Pharmacodynamics and pharmacokinetics are the two branches of pharmacology. Remember, pharmacokinetics describes what the body does to the drug through absorption, distribution, metabolism, and excretion (ADME), whereas pharmacodynamics describes what the drug does to the body.
When selecting drugs and determining dosages for patients, it is essential to consider individual patient factors that might impact the patient's pharmacokinetic and pharmacodynamic processes. These patient factors include genetics, gender, ethnicity, age, behavior (ie diet, nutrition, smoking, alcohol, illicit drug abuse), and/or pathophysiological changes due to disease.
ASSIGNMENT
Directions: For each of the scenarios below, answer the questions using your required learning resources, Medscape, and clinical practice guidelines (ie AHA, ACC, ADA). When recommending medications, write out a complete prescription for each medication. What order would you send to a pharmacy? Include drug, dose, route, frequency, special instructions, # dispensed (days supply), refills etc. Also state if you would continue, discontinue or taper the patient's current medications (if applicable). Use at least 3 sources for each scenario and cite sources using APA format.
Case Scenario 1
What are the errors in the following prescriptions (1 per prescription)? Rewrite each prescription correctly. What is each medication classification? What is the mechanism of action (MOA)?
metaprolol succinate ER 50 mg PO daily #30 1 RF
amiodarone 75 mg PO daily #30 1 RF
amlodipine/hydrochlorothiazide (Lotrel) 5 mg/12.5 mg PO daily #30 3RF
hydralazine/isosorbide mononitrate (BiDil) 37.5 mg/20 mg PO every 8 hours #90 1 RF
clonidine patch (Catapres-TTS-1) 0.1 mg/day apply one patch to skin and replace every 3 days #10 patches 0 RF
Case SCENARIO 2
Does verapamil have a high or low first pass effect? Please discuss why this is important to know and how it relates to bioavailability. Define these two terms. What route has 100% bioavailability? In addition to parenterally, how can verapamil be given to counter the first pass effect? Write a sample prescription for this medication.
Case SCENARIO 3
Where are the majority of cytochrome P450 (CYP) enzymes located? Using the Medscape pill identifier, enter the following characteristics to identify the medication AND strength. What CYP enzyme metabolizes this medication? How can this information be applied to medication therapy management? Write a sample prescription for the identified medication and strength. What are goal cholesterol levels and (Coronary Artery Disease) CAD risk factors?
Imprint (ATO 40) Shape (Oval) Color (White) Form (Tablet) Scoring (None)
Case SCENARIO 4
RT is a 54-year-old female presenting with blood pressure today of 135/90 HR 80 RR 15. Her last visit to the clinic 3 months ago shows a BP of 134/88. She is currently taking metformin 500 mg PO BID with meals, ibuprofen 600 mg PO TID for back pain, and duloxetine 60 mg PO daily. What is her goal blood pressure? What medication would you prescribe and how would you improve her