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In humans, the genes for red-green color blindness (R = normal, r = color-blind) and hemophilia A (H = normal, h = hemophilia) are both X-linked and only 3 map units apart. Suppose a woman has four sons, and two are colorblind and have hemophilia and two have normal color vision and normal blood clotting. What is the probable genotype of the woman? The answer is HR/hr, but I need an explanation.
What is the expected frequency of the AB haplotype if the frequency of the A allele at locus 1 is symbolized as p and the frequency of the B allele at locus 2 is symbolized as r?
What effect might this have on cell lineages during development. Describe the physical changes that would occur in SIM medium if you inoculated an organism that was negative for hydrogen sulfide but positive for indole production and motility.
The complement system and innate immunity via Toll-like receptors play critical roles in immune defenses against pathogens. These two systems traditionally have been considered to be separate.
In the Law of Particulate Inheritance, what are the particles that is being inherited.
What would be the expected frequencies of the homozygous dominant, heterozygous, and homozygous recessive after 100 generations.
Consider the following two genotypes: AABB, aabb where A and B are dominant and a and b are recessive.
Assume your TA gives you a bacterial culture and claims there are 4.8 x 107 bacteria/mL in the culture. To check up on her, you prepare serial dilutions of 10-4 - 10-7.
Why is the amount of oxygen consumed so much greater than the amount require to oxidize the added oxaloacetate or malate completely.
Suppose that a population of 1500 Tasmanian Devils is in H/W equilibrium for a gene that determines fang length. The allele for long fangs is dominant to the allele for short ones.
Discuss each parameter (Vmax and Km) as to how it relates to the ability of mutant kinesin to bind to the microtubule and hence, to transport proteins along the neuron.
How is the process of opening up the DNA helix and making mRNA similar to and different from DNA replication and a full, bidirectional, replication bubble?
A simple batch fermentation of an aerobic bacterium grown on methanol gave the given experimental results:
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