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Assume the following:
• There are approximately 3,000,000,000 base pairs in the mammalian genome (genes constitute only a small portion of this total).• There are approximately 10,000 genes in the mammalian genome.• A single gene averages 10,000 base pairs in size.
In the mammalian genome:1. How many total base pairs are in all the mammalian genes?
2. What proportion (%) of the total genome does this represent?
3. What is the probability that a random mutation will occur in any given gene?
4. Only 1 out of 3 mutations that occur in a gene result in a change to the protein structure. What is the probability that a random mutation will change the structure of a protein?
Provide a brief description of the experiment about cloning a portion of the bacteriophage Lambda genome into a plasmid using previously published works and cite them.
A generalized transducing phage is used to transduce an a-b- c- d- e- recipient strain of E. coli with an a+ b+ c+ d+ e+ donor.
Why would someone use a split ratio as opposed to making a cell count? What is the major drawback to performing a split ratio?
The -10 and -35 sequences in bacterial promoters are separated by about two turns of the DNA double helix (remember genetics?). How do you think transcription would be affected if the deletion were introduced such that the -35 sequence was moved to -..
Each chromosome consists of only one centromere, but during certain times in the cell cycle could consist of two DNA molecules (sister chromatids). If a cell in G1 of interphase has 8 chromosomes, then in G2 of interphase, how many chromosomes AND..
Both endocrine and nervous system are major regulating systems of the body; however, the nervous system has been compared to any post mail delivery system and the endocrine system to the pony express. In brief explain this comparison.
How would you interpret a negative Slide Test and a positive Tube test using the same organism? What is the role of sterile saline plus organism on the Slide Test?
The phylum Arthropoda includes four major lineages: cheliceriforms (also called chelicerates); myriapods; insects and their relatives (together called hexapods); and crustaceans.
What were the key innovations that allowed adaptive radiation of modern plants? Why are bryophytes considered to be primitive plants? Why do bryophytes and ferns need water for reproduction?
Find a virus capsid containing vimentin, your protein of interest, gets into the cell nucleus and is broken down with the DNA being released.
Describe and diagram the synthesis of a secretory protein on membrane-bound, Er-localized ribosomes.
If the spinal lemniscus is cut on the right side of the medulla, what would be the clinical outcome?
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