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Why can't a monomeric receptor tyrosine kinase recruit proteins to the receptor? What would happen if the GTP-ASE protein(GAP) were inhibited?
EDIT: I have found the answer to the the second question posted here. However, I believe I have discovered the answer to the first question, but I fail to understand it. Can someone simplify it into english?
The most abundant class of enzyme linked receptors are receptor tyrosine kinases which respond to signal molecules call for proliferation, differentiation, or survival of different cell types. In response to ligand binding, the receptors oligomerize and the cytosolic tails-which contain tyrosine kinase activity-phosphorylate each other's tyrosine residues. This autophosphorylation increases the kinases activity of the receptor, and creates binding sites for different proteins. The signaling receptor proteins require phosphotyrosine to bind; hence they do not interact with the inactive monomeric receptor.
What is most likely genotype of the father? Mother? If the seventh child had blue eyes what could you conclude about parents genotyoes. What possible dissimilarity between these forms would give chemists a clue that open-chain form was not present.
What will be the sex ratio in the offspring of a cross between a male that is heterozygous for lethal allele and a normal female.The classes of RNA molecules is linked with proteins.
Two strands of a DNA molecule are radio-labeled such that each strand can be uniquely identified. After three bouts of replication, how many new molecules of DNA are formed? How many strands of DNA are radio-labeled? Are both radio-labeled strands..
What does this show about the relation between voluntary and involuntary reflex movement. If the bacteriorhodopsin molecules were randomly oriented, would you expect ATP to be synthesized? Give details about the answers.
On average, how many complete turns would be in each chromosome. The human gametes have about 3 billion bp of DNA in their chromosomes.
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Represent graphically the relation between melting temperature and the G-C content of DNA. Construct relations for dependence of melting temperature of a 30 bp DNA duplex on the G-C content.
If two organisms each with the genotypes TtGg mate what is the probability that they will produce a child with the dominant phenotype for height and recessive phenotype for colour.
Aspirin has a pH of three. Some people who take large amounts of aspirin (for example, for arthritis) take a pill that combines aspirin with Maalox. What is the reason for this combination.
RNA helicases are required for translation and multiple steps of splicing. What enzymatic activity do these enzymes possess? How is this activity possible to be used in: translation or Splicing.
An organism has a diploid chromosome number of 12. How many chromatids will be visible during metaphase of mitosis? How many chromosomes will be visible at the end of anaphase in mitosis? For the similar organism, how many chromosomes will be present..
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