What is the mechanism of action of naloxegol

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Problem

A 60-year-old male with a history of chronic back pain secondary to lumbar spinal stenosis has been on long-term opioid therapy with oxycodone. He presents to the clinic complaining of severe constipation that has not responded to over-the-counter laxatives, including bulk-forming agents, osmotic laxatives, and stool softeners. His physical examination is unremarkable except for distended abdomen with palpable stool. The PA decides to prescribe naloxegol to manage his opioid-induced constipation (OIC). Get the instant assignment help. What is the mechanism of action of naloxegol that makes it suitable for treating OIC in this patient?

Reference no: EM133867219

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