What is the expected plasma drug concentration

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Problem

A drug has an elimination half-life of 8 hours and follows first-order elimination kinetics. If a single 600-mg dose is given to an adult female patient (62 kg) by rapid IV injection, what percent of the dose is eliminated (lost) in 24 hours assuming the apparent Vss is 400 mL/kg? Get the instant assignment help. What is the expected plasma drug concentration (Cp) at 24 hours postdose?

Reference no: EM133870464

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