What is the cancer risk of lifetime exposure utilizing adafs

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Reference no: EM133739723

Problem

Consider a scenario of exposure to a carcinogen with a mutagenic mode of action. Suppose the oral cancer slope factor derived from a typical animal study (i.e., where dosing begins after puberty) is estimated to be 0.03 per mg/kg-d, and the exposure rate remains constant throughout life at 0.003 mg/kg-d (this is equivalent to saying the daily average of lifetime dose rate is equal to 0.003 mg/kg-d). What is the cancer risk of lifetime exposure utilizing the ADAFs?

Reference no: EM133739723

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