Reference no: EM133984819
Questions:
- What is meant by the term Cell cycle?
- What are the phases of cell cycle
- List the key features for the each phases of cell cycle
- What is a G0 Phase? What is the biological significance of G0 phase?
- What are Check points in cell cycle?
- What are differences between a proto-oncogene and an oncogene?
Clearly state the roles of following modification as and the enzymes that mediate these modifications:
- Lysine acetylation
- Lysine methylation- difference between H3K4methylation and H3 K27 methylation. (H3K4 and H3K27 mean Lysine at positions 4 and 27 on the histone H3 protein)
- Serine/threonine/tyrosine phosphorylation
- Lysine Ubiquitination
As described on one of the slides - explain the generation of polyps then colon cancer- which mutations are involved and at what stages?
What are the two proteins that regulate cell cycle?
Which CDK and Cyclin Partnerships are involved during:
What is meant by the term gene expression
What is meant by the term regulation
What are the stages in which a gene could be regulated
What is an activator how does it act?
What is a repressor how does it act?
Why does DNA methylation occurs and on which nucleotide
What does presence and/or absence of tryptophan do to the tryptophan synthesizing gene
What does presence and absence of glucose and lactose do to the lactose promoter
Give an example of how alternative splicing results in expression of different proteins in two different organs
What is miRNA, RNA interference and SiRNA in gene expression
What is essential for a ribosome to control translation on mRNA in term of start site orientation.