Reference no: EM133312219

Assignment:

1. What is a knockout mouse?

A. Mouse that is genetically engineered to be aggressive (so it knocks out other mice)
B. Mouse that has dark circles around its eyes
C. None of these
D. Mouse that has an existing gene deleted or replaced
E. Mouse that is easier to knock unconscious for surgery

2. Is it surprising that some drugs can cure cancer in mice but not in humans?

A. No - Humans and mice evolved different life history traits
B. Yes - both mice and humans are mammals so share fundamental traits of mammals
C. No - Humans and mice evolved separately in very different environments
D. None of these
E. No - Humans are much larger than mice
F. All of the No answers are correct

3. Humans are _____________ times larger than mice

A. 25
B. 250
C. 2500
D. 25000

4. Using the equation Basal Metalbolic Rate = 70 * (mass in kg)0.75, what is the metabolic rate for a 150 lb person? You can round your answer to the nearest whole number. (Hint: look at the units!)

A. 1658
B. 1568
C. 1640
D. 3000
E. 2000

5. How do mice and humans differ in their ability to handle ascorbic acid (vitamin C)?

A. Humans need ascorbic acid supplements while mice can produce their own ascorbic acid
B. Mice get most of their ascorbic acid from unprocessed grains and cereals
C. Mice need ascorbic acid supplements while humans can produce their own ascorbic acid
D. Mice ancestors' diets were low in ascorbic acid, so mice evolved to no longer need ascorbic acid
E. Humans and mice handle ascorbic acid similarly

6. Mice and humans are biologically similar in that they both have an appendix.

True
False

7. How are mice adapted to their higher risk of respiratory diseases?

A. Mice have teeth to fight off other animals who may have zoonotic (animal-borne) diseases
B. They have larger lungs for their body size, so have more surface area to breathe if their lungs become impacted by disease
C. None of these
D. Mice are immune to zoonotic disease from other rodents
E. Mice have large amounts of lymphoid tissues associated with their lungs to help fight off pathogens

8. The author includes a quote from Monod and Jacob's:

"Anything found to be true of E. coli must also be true of elephants."

Which of the following would not support this statement?

A. Both E. coli and elephants are organisms made up of one or more cells

B. None of these

C. Many organisms have similar traits because they evolve under similar environmental conditions (e.g. torpedo body shape for animals that swim underwater)

D. Ultimately, elephants and E. coli have the same goals: acquire resources to survive, and reproduce to pass on their genes

E. Drugs that cure mouse cancer are not capable of curing human cancer.

9. Humans and mice differ in how their bodies maintain memory T cells. If you recall, memory T cells are antigen-specific cells that remain long-term after an infection has been eliminated. What is the most likely cause for this difference?

A. Humans and mice have drastically different lifespans, so human T cells need to "remember" for longer timescales than mice T cells

B. Humans have bigger T cells than mice

C. None of these

D. Humans get more intense infections than mice

E. Mice tend to get drastically different infections than humans do.

10. Why might carrying out research on only young mice be a problem?

A. These mice aren't old enough to reproduce

B. It biases the research to only be able to draw human comparison to young people

C. Young mice are more resource-intensive, so are more expensive to raise

D. Young mice prefer mixed-sex groups over single-sex groups

E. It is damaging to the mice