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When adrenaline binds to adrenergic receptors on the surface of a muscle cell, it activates a G-protein, initiating a signaling pathway where the activated G α subunit activates adenylyl cyclase, increasing cAMP levels in the cell; the cAMP molecules then activate a cAMP-dependent kinase that, in turn, activates enzymes that result in the breakdown of muscle glycogen, thus lowering glycogen levels. You obtain muscle cells that are defective in various components of the G-protein signaling pathway. Indicate how glycogen levels would be affected in the presence of adrenaline in the following cells. Would they be higher, lower, or the same as normal cells that are treated with adrenaline?
o In cells that have a G α subunit that cannot hydrolyze GTP but can interact properly with G β and G γ.• In cells that lack the receptor?• In cells that lack adenylyl cyclase?• In cells that lack cAMP phosphodiesterase?
What are three malignant properties of cancer that distinguish them from benign tumors?
Explain the study of hypothesis? Specify the outcome variables and also state how they were measured? Explain the study factors (exposures) and how were they measured?
Think about an interaction between two mutually-inhibiting proteins with concentrations x and y, given through the differential equations.
Your working at a remote field station and you've been given a container of undentified mostly microscopic. Your job is to determine if the organisms are bacteria, unicellular algae, or protozans.
You are observing an enzyme driven reaction. to the reaction mixture you add a chemical X which inhibits the reaction. If you add more substrate, the reaction rate approaches the Vmax pf the uninhibited reaction. Furthermore, the structure of X is..
Assume you incubated 10ml of a solution containing 0.15M G6P overnight at 25 degree C with the enzyme phophoglucose isomerase. How many millimoles of F6P will be in the 10ml solution in the next morning.
Which of the following controls climate or weather?
The genes for body color and wing size in Drosophila are on the same chromosome and forecast the ratios of the following phenotypes among the offspring,
A well-kept secret is that the Philly Phanatic is really an F1 organism, the product of a homozygous dominant father and a homozygous recessive mother. The alleles of interest are: G= green fur, g=pink fur, H= horn-shaped snout, h=violin-shaped sn..
What are the different phospholipases that act to hydrolyze the ester linkages of the groups attached to the various carbon atoms of glycerol? At which carbon atom of glycerol are you most likely to have arachidonate bound?
Margo recently began working out and jogs 3 times a week. After her jogs she is breathless and her muscles ache. What has happened inside margo's skeletal muscle cells. If Margo continues what changes would occur in her muscles.
Was evolutionary pressure that contributed to the echinoderm nervous system development likely due to selection for those animals capable of forward locomotion?
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