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Q1. The venom of many cobras contains a potent neurotoxin that binds to ligand-gated Na+ channels, causing them to open. Unlike ACh, that binds to and after that rapidly unbinds from ligand-gated Na+ channels, the neurotoxin tends to stay bound to ligand-gated Na+ channels. How does this neurotoxin affect the nervous system's ability to stimulate skeletal muscle contraction? How does it affect the capability of skeletal muscle fibers to respond to stimulation?
Q2. Tay-Sachs disease is caused by loss-of-function mutations in a gene on chromosome 15 that encodes a lysosomal enzyme. It is inherited as an autosomal recessive condition. Among Ashkenazi Jews of Central European ancestry, about 1 in 3600 children is born with the disease. What fraction of individuals in this population are carriers?
Results of this analysis show that one of the most rapidly reassociating classes of DNA is substantially reduced in the older individual with respect to the 2 year-old. How can you describe this finding.
The patient lives near the San Luis Rey River and has no history of foreign travel, blood transfusion, or intravenous drug use. What is the disease? How was it obtained.
Explain at least one historical extinction with parallels to the extinction threats facing the bog turtle. When allosteric effector X binds to enzyme #1, enzyme stops working. However, the speed of reaction can be altered by adjusting the concentrati..
What percent of the population are homozygous dominant. What do you assume would be the effect on the switch of reversing orientation of one of the hix sites.
Explain why there are no male offspring with the allele combinations
Which of the follow is NOT a function of meiosis. Generation of genetic diversity by crossing over.
Those that live in tropical climates like the savannas of Africa are usually much smaller than the ones that live in arctic regions like Lapland.
What could be expected phenotypes, and in what number will the y be expected? Suppose no linkage.
What do you think is the most probable mechanism of browning? If a patient's resting cardiac output is 5.6 l/min and on a stress test she elevated her heart rate to the highest of 176 beats/min with a stroke volume of 115 ml/beat, what is her cardiac..
Analyze the stressors employees might experience as a result of the underperforming economy and current retraction of business, and make at least three recommendations for how approximately any leader or manager might help mitigate those stressors. S..
Calculate how the permeability of each is altered when the pH is reduced to 1.0, a value typical of the stomach.How to demolish the function of this protein.
Social media strategy implementation and evaluation
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