Reference no: EM133979916
Assignment:
You work for a pharmaceutical company where you are assigned the task of creating new drug therapies to treat thyroid disorders such as hyperthyroidism (high levels of T3 and T4) and hypothyroidism (low levels of T3 and T4). Your team has designed a few drugs, and your job is to identify which drug(s) would be successful in treating thyroid disorders based on your knowledge of thyroid hormone synthesis. Below is the list of drugs your team designed (all of these are hypothetical drugs).
[1] Explain the pathway and negative feedback loop involved in thyroid hormone production beginning with the hypothalamus.
[2] What factors can cause hyperthyroidism? What factors can cause hypothyroidism?
[3] Identify the drug(s) that would be successful in treating hyperthyroidism and hypothyroidism. Explain why and how they would be successful.
Peroxidine: A drug that inhibits thyroid peroxidase from functioning
Cimigine: A drug that inhibits potassium/iodine cotransporter
Iodimine: A drug that inhibits iodinase from functioning
Aldosine: A drug that inhibits production of angiotensinogen from the liver
Aldoramine: A drug that inhibits sodium/iodine cotransporter
Thyromine: A drug that stimulates thyroglobulin production
please use references and cite everything! And number all the answers in their order.
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