What does this pattern reveal about function of his b cells

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Reference no: EM133951081

Problem

A. Despite being fully vaccinated, this child clearly has poor protection against infections like pneumonia and ear infections. What does this tell you about his ability to mount an antibody response?

B. His serum immunoglobulin panel shows very low IgG and IgA but elevated IgM. What does this pattern reveal about the function of his B cells? His T cells? Get the instant assignment help.

C. How do the elevated acute-phase proteins (CRP, SAA, complement C3) fit into the clinical picture, and why do they not necessarily indicate a healthy adaptive immune system?

D. On physical exam, the patient's tonsillar tissue was absent. What does this finding suggest about his underlying immune defect, and how does it connect to his B cell function? What type/class of lymphoid organs are the tonsils?

E. Which arm(s) of the adaptive immune system are impaired in this patient? Cell-mediated, humoral, or both? Explain. Is there any evidence of an issue with his innate immune system?

F. What is your leading diagnosis? What findings from the history, physical exam, imaging, and laboratory studies provided the most information for you to reach a diagnosis? What additional laboratory tests (if any) would you order to confirm your diagnosis?

Reference no: EM133951081

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