Reference no: EM132369759
Association of Vascular risk factors to Cognitive impairment in Parkinsons disease.
KEYWORDS USED FOR PUBMED SEARCH:
1) What are the vascular risk factors used for searching :
- AGE
- OBESITY/BODY WEIGHT /BMI
- GENDER/SEX (M/F)
- SMOKING/NICOTINE
- ALCOHOL
- CHOLESTROL/LIPID
- HOMOCYSTEINE
- CYSTATIN-C
- URIC ACID/URATE
- HYPERTENSION or SUPINE HYPERTENSION
- DIABETES
- WHITE MATTER HYPERINTENSITY /CHANGES /MRI
- PULSE PRESSURE
- CAROTID ARTERY THICKENING .
- METABOLIC SYNDROME.
2) Other factors considered were :
- LOW SUGARS/HYPOGLYCEMIA/LOW GLUCOSE
- HYPOTENSION/ORTHOSTATIC HYPOTENSION
- AUTONOMIC/DYSAUTONOMIA.
3) Only Case control and Cohorts were considered which has OR/RR/HR with 95% CI which lead to final 25 papers which is ready for statistics now .
4) I will provide the Excel sheet with headings for data extraction .
5) Once care full data extraction is over I need the excel sheet again to show to my mentor .
6) Once approved need to go for statistical analysis by Strata 15.
Requirement for metanalysis for VASCULAR RISK FACTOR IN ASSOCIATION WITH COGNITIVE IMPAIRMENT (MCI (Mild cognitive impairment) ) or Dementia and anything related to memory impairment in all the 25 papers including UPDR3 ,LEDD and others which can be extracted related to my topic and anything related to factors which can cause vascular involvement causing problem in cognition in Parkinsons ( Max data extraction more the better )
Case 1: Meta-analysis of risk factors for Parkinson's disease dementia by Yaqian Xu, Jing Yang and Huifang Shang
Case 2: Modifiable Risk Factors for Cognitive Impairment in Parkinson's Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies
Attachment:- Study Design.rar
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