Transplant the distal part of an old wing bud

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Reference no: EM133932414

Questions

1. When the distal part of an early wing bud (including the distal mesoderm and the apical ectodermal ridge) is transplanted to a late wing bud (replacing the host distal tissue), complete new limb structures including stylopod, zeugopod and autopod are made beyond those already specified in the host.

Please, give an interpretation of the result of this experiment according to a) the progress zone model.

The two-opposite gradient model of proximo-distal patterning of the limb. You can use drawings if you wish.

2. What would you expect to observe if you perform the reverse experiment: transplant the distal part of an old wing bud (mesoderm + AER) to an early wing bud (replacing the host distal tissue)? Please explain the result according to the two-opposite gradient model. You can use drawings if you wish.

3. What would you expect to observe if instead of grafting an AER + distal mesoderm, you were transplanting the AER alone on a late or an early wing bud, respectively? Please explain the result of this experiment.

Reference no: EM133932414

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