Summarize article-mutant causes deregulated differentiation

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Summarize the following article in two pages.

Speak and list explicitly the main + interesting facts about this research experiment.

Explain the biological mechanism behind this study.

Include a one page research proposal about potential future studies.

Article- A c-Myb mutant causes deregulated differentiation due to impaired histone binding and abrogated pioneer factor function by Bettina M. Fuglerud, Roza B. Lemma, Pimthanya Wanichawan, Arvind Y. M. Sundaram, Ragnhild Eskeland and Odd S. Gabrielsen

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Mutation is nothing but the alteration in genomic sequence in organism and by inducing these mutations one can treat some life threatening chronic conditions. The current paper deals about the inducing mutation to treat serious Hematopoietic conditions like leukemia and their pioneer transcription factors and the mechanism of its action. The paper also talks about the research models about high and low levels of C-Myband their effects in causing the disease. The paper was prepared in Micro soft office document

Reference no: EM131684574

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1/18/2018 5:21:40 AM

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12/21/2017 4:35:08 AM

Need at least 90% on the assignment, please do appropriately thank you 1. Please state explicitly the important/interesting findings of the study 2. The research proposal must be original/new(do not refer to "future studies" section). Must also be longer (requested a page and it's only a paragraph - the document is only 2 pages, whereby I requested 3 initially). Also, provide potential experimental questions. 3. Please mention what are proteomics & the role it plays in the mechanism. The initial request is the project for 3 pages. 2 allocated to the summary and 1 to the research proposal and the proposal is original so do not refer to "future studies" refereed in the discussion.

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