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Spherocytosis is an inherited blood disease in which the erythrocytes (red blood cells) are spherical instead of biconcave. This condition is inherited in a dominant fashion, with SPH (the mutant allele) dominant to SPH . In people with spherocytosis, the spleen "reads" the spherical red blood cells as defective and removes them from the bloodstream, leading to anemia. The spleen in different people removes the spherical erythrocytes with different efficiencies. Some people with spherical erythrocytes suffer severe anemia and some mild anemia, yet others have spleens that function so poorly there are no symptoms of anemia at all. When 2400 people with the genotype SPH SPH were examined, it was found that 2250 had anemia of varying severity, but 150 had no symptoms. a) Does this description of people with spherocytosis represent incomplete penetrance, variable expressivity, or both? Explain your answer. b) Can you derive any values from the numerical data to measure penetrance or expressivity?
The numbers indicate the numbers of asci of each type. Determine the correct gene order and all gene to gene and gene to centromere map distances.
Create a cohesive paragraph about proteins explaining their chemical content, structure, and general properties. In discussion, describe the general chemical structure of an amino acid.
Describe the structure and function of the three forms of RNA determine the primary structure of polypeptide chains during translation.
Cephalochordates and placental mammals both have microlecithal eggs, yet mammalian early development resembles that of birds more than that of amphioxus.
What does narrow sense heritability (h2) estimate? a. The proportion of phenotypic variation that is due to total genetic variance b. The proportion of phenotypic variation that is due to interactive variance.
The following cross involving three genes was performed: Aa Bb Cc x aa bb cc, and the phenotypes and number of progeny are shown below. Each pair of alleles exhibits simple dominance and recessiveness.
assume that the mutation that produces abnormal dynein occurs on the gene which codes directly for dynein. very briefly describe each of the possible mutations that might be the cause of the abnormal dynein of kartageners' syndrome.
Hand draw the backbone conformation of Alanine Dipeptide.
assume the responsibility of the director of environmental protection agency epa. list the most important actions for
1)construct a concept map of evolution using the following terms: evolution, allele frequency, mutation, natural selection, sexual reproduction, environment, genetic diversity, sexual selection, genotype, adaptation?
Explain why type AB+ blood may be called the "universal recipient" for blood transfusions. Explain why this would not be true if the transfusion required 6 units (about 3 liters) of blood.
Explain the difference between and antigen and an antibody. How do they relate to blood typing?
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