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1. Assume you identify a recessive mutation in the AP endonuclease in yeast. During the diploid phase of their lifecycle, the yeast are viable but haploid strains die rapidly. Why might this be?
2. (a). What is the difference between germline and somatic mutations? (b) name at least one way that each of these types of mutations can affect human health.
3. (a) What type(s) of DNA damage is/are repaired by the non?homologous end?joining pathway? (b)Describe this repair process. (c) Explain why non?homologous end?joining is considered an error prone DNA repair pathway? (d) What mutations are typically associated with non?homologous end joining?
While two monohybrid round squashes are crossed, the offspring ratio is ¼ flat, ½ oblong, ¼ round. Squash shape is therefore controlled by incomplete dominance. What offspring ratio would you expect from a cross between a plant with oblong fruit and ..
Gene frequencies for the ABO alleles vary geographically. For example the I^A allele makes up nearly 50 percent of the genes for blood type among Australian Aborigines, about 25 percent in Central Asian populations,
Explain normal regulation of blood glucose through the pancreatic hormones. How is this altered with Diabetes?
What F1 phenotypic and genotypic ratios are formed from this cross . how may this affect the rate of protein synthesis.
If we have a dsDNA molecule and we require an ssRNA molecule, which of the two DNA strands will have the same sequence as the RNA molecule?
When O2 binds to heme in hemoglobin, the is drawn into the plane of the porphyrin, causing conformational change that is transmitted to adjacent subunits.
The bacteria are allowed to grow overnight and are streaked on a plate using a technique that produces isolated colonies that are clones of the original. Samples of these colonies are then grown in four different media: nutrient broth plus ampicillin..
What is the possibility that their next child will show both defects? Demonstrate the work.
When the differential is obtained what is the meaning of the percentage of.define What are the clinical scenarios.
Suppose you are given a mixture of proteins that you examine by standard 2-D electrophoresis, with the following results for isoelectric points.
What proportion of progeny would PHENOTYPICALLY resemble.
In a separate piece of paper, make a simple family tree for a couple showing children, and lineages from two children showing grand children, great grandchildren, great great grandchildren, and great great great grandchildren.
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