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Question 1
What effect would a drug that either dramatically reduced or enhanced the fidelity of a viral RNA polymerase have on the survival and fitness of a virus in a population? Explain Why? Are there currently examples of such drugs? How do they work?
Question 2
Read the review by Feschotte and Gilbert on Endogenous Retroviruses (ERVs). What are ERVs and why are they important? What impact have they had on viral and human evolution?
Question 3
Read the perspective by Arien et al about HIV evolving to a less virulent form. What are the mechanisms by which HIV may evolve to a less virulent form? What are the arguments for or against attenuation?
Question 4
Read the article by evolutionary biologist Paul Ewald entitled "Guarding against the Most Dangerous Emerging Pathogens: Insights from Evolutionary Biology." Describe his concepts on the evolution of virulence in terms of a virus. Use specific examples of viruses we have studied that demonstrate the concepts he outlines.
Question 5
Watch the recent "Coffee House Presentation" video entitled " Adaptation and Evolution: The Life of an RNA Virus." (The first 20 mins are the presentation and the rest is an excellent Q&A).What is "metagenomics" and how can it be used to detect and prevent emerging viral infections? Why is zoonotic virus transmission the reservoir for emerging diseases? What animals are commonly reservoirs for transmissioto humans? Why?
Verified Expert
please describe how one might search for chemical structure biologic function relationships involving small molecular
The Cleaver family awaited the birth of Claudette's puppies with anticipation. But shortly after standard poodle gave birth to six pups, two of them.
Complete the Punnett squares for a cross between the male with blood type B and a female with blood type AB. Build two Punnett squares and answer the following given questions about them.
Which plant division produces naked seed?
What is peristalsis.
A spheroidal bacterium with a diameter of 1 um contains two molecules of a particular protein.
Genes A, B, and C are linked on a chromosome and found in the order A-B-C. Genes A and B recombine with a frequency of 8%, and genes B and Crecombine at a frequency of 24%.
Utilize the words mesoglea, epidermis, gastrodermis, polyp, medusa, and gastrovascular cavity to describe the differences between the two forms of phylum cnidaria.
What is the gene order? What are map distances in recombination units?
Describe why heritablility only applies to population (not individuals or species), and how heritability can change without any genetic change occurring.
How various molecules of ATP are USED UP in the glycolysis pathway.
Which of the following describes the basic function of a coenzyme?
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