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Question 1: Explain why only certain cell types are permissive for transcription of HIV proviral DNA. What cellular factors are involved and why?
Question 2: What are the selective advantages and disadvantages for DNA viruses in relying on host cell apparatus for production of mRNAs and replication of their genomes? Give examples of host cell apparatus required.
Question 3: DNA viruses generally possess a precisely ordered and temporal sequence of transcription of viral genes. Why is this control necessary and beneficial to the virus? By what molecular mechanisms do viral proteins help mediate this control? Give specific examples.
Question 4: DNA viruses are heavily reliant on the host for providing factors required for replication. Replication of eukaryotic DNA is a very precisely regulated process and normally only occurs prior to mitosis. Therefore, viruses have evolved a number of mechanisms for enabling viral DNA synthesis when the host cell is in the Go state. Describe elements of one such mechanism and why they are required for viral replication. What are the advantages for the virus?
Question 5: Many DNA viruses possess latent infectious cycles. What are the characteristics of a latent infection and how does a latent virus alter both its production of RNA and replication to maintain the latent infection?
Question 6: What are the complications/obstacles for a single stranded DNA virus to replicate its genome. Describe mechanisms a specific virus uses to overcome these obstacles.
how can a G-protein open an ion channel either directly or through a protein kinase enzyme?
Fatty acid beta oxidation generates both NADH and FAD2. These are oxidized in the electron transport chain through
How is geological energy different from biological energy. Charlie has the blood test that shows a normal level of LDLs other than an elevated level of HDLs in his blood. Because his family has a history of cardiovascular disease, he wonders if he mu..
When is double strand break repair important in bacteria? What about eukaryotes? (in other words, what are the situations when you would expect to get ds DNA breaks in each type of organism?)
q1. a marine biologist has dredged up an unknown animal from the seafloor. describe some of the characteristics she
Two new chemicals have just been made by one of our colleagues in the medicinal chemistry area. The discoverer thinks that these chemicals will improve memory, so we test these drugs called A and B.
A cross ia made in tomatoes between a female plant from a pure line that is trisomic for chromosome 6 and a normal diploid male plant that is homozygous for the recessive allele for potato leaf (pp).
Female Drosophila heterozygous for three recessive mutations e (ebony body), st (scarlet eyes), and ss (spineless bristles) were testcrossed, and the following progeny were obtained: Phenotype Number wild-type 67 ebony 8 ebony, scarlet 68 ebon..
Leukocytes (white blood cells) normally move into tissues that have been damaged so that they can heal the damage (repair blood vessels, eradicate bacteria, etc.). How do they move from the blood stream into the damaged tissue? Include in your ans..
What is the probability that the first child of Tom and Terri will be Rh- and have elliptocytosis?
Describe how the sympathetic nervous system response and the release of renin by the kidneys help to reestablish the MAP back to a normal level.
Consider a mainland-island migration scenario where two alleles are segregating and the observed frequencies of heterozygotes are such that H=.32 for the mainland and H=.5 for the island. (These are the values of heterozygosity) What are Pisland a..
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