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Q1. Mutations in the genes that encode certain mitochondrial proteins are associated with a high incidence of some types of cancer. How might defective mitochondria lead to cancer?
Q2. Suppose archaeologists discover human skeletal remains in Ethiopia. Examination of the bones suggests that the remains represent four types of individuals. Two of the skeletons have bone densities that are 30 percent less than those of the other two skeletons. The skeletons with the lower bone mass also have broader front pelvic bones. Within the two groups defined by bone mass, smaller skeletons have bones with evidence of epiphyseal plates, but larger bones have only a thin line where the epiphyseal plates should be. Give the age group and gender of the individuals in the find.
You are working with an enzyme that catalyzes the deamidation of Gln residues in proteins. You have developed two different tripeptide substrates for the enzyme.
Draw the structure of the dipeptide GLY-HIS. What is the charge on the peptide at pH 5.5? And at pH 7.5?
The ion gradients maintained across the plasma membranes of most cells play a significant role in cellular energetics. Ion gradients are often either generated by the hydrolysis of ATP or used to make ATP by the phosphorylation of ADP.
A unit of enzyme activity is usually defined as the amount of enzyme converting 1µmol of substrate per minute under optimum conditions. If the reaction cuvette had a volume of 1mL, calculate how many enzyme units were present in 10µL of enzyme ext..
If the control is solid and an inoculated tube is liquid, is it acceptable to read the results before the complete incubation time has elapsed? Why or why not.
Calculate the standard free energy change for the conversion of D-glucose from alpha to beta form at 40 degrees C, if relative amount of alpha-glucose at this temperature is 36%. Please explain step-by-step.
Why is replication host range important when considering horizontal gene transfer mediated by plasmids.
In a small population of alpine foxes, you observe increased ear length over a 10-years period, increase in ear length is advantageious in this population
Write a short description of the lipid bilayer in the biologicalmembrane. what do you understand by fluidity of the membrane
The membrane vesicles are next washed, the membranes solubilized and the proteins denatured and analyzed by SDS gel electrophoresis and Western blotting using polyclonal antibodies against glycophorin A, an erythrocyte plasma membrane protein.
If you have 10 different amino acids and want to make a polypeptide chain of 6 amino acids, how many theoretical combinations of amino acids could you make?
At the startingof the spring, Dr. Peter Erlenmeyer notices that there is an equal distribution of long and short stemmed dandelions in the vacant lot across the street from his house as well as in his own backward and Explain how the information stor..
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