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Q. 1. Based on the structure of individual keratin subunits, why would a single point mutation in the alpha-helical region of the monomer result in a defect in the polymer?
2. An alternative model is that the mutations cause defect intermediate filaments with defective structure that causes problems in the capability of motor proteins to transport material on these filaments. Is this a plausible model? Why or why not give reason?
A human cell has 10^14 cells and each human cell has about 6.4x10^9 nucleotide pairs of DNA. What is the length of double helix that could be formed from this amount of DNA in a human individual?
Design an experiment in which you will test the effect of an acidic fluid on enzymatic activity. (Recall: enzymes are proteins.) To complete this project.
Purines and pyrimidines play crucial part in cellular energy systems signaling and in the production of DNA and RNA.
The matrix used in experiment has a fractionation range 20000 to 5x10^6 Daltons. Would you see this matrix purify a plasmid that had a molecular weight.
Discuss the most important SIMILARITIES & DIFFERENCES between DNA repication and RNA trnascreption?
Modern theory suggests that the early pre-life atmosphere on Earth was a reducing one. Why is it believed that oxygen was not present as life formed on Earth.
What is t-cell mediated suppression? I have been trying to read about it and understand what it is.. but everything I read it doesn't really make sense to me.... and what mechanisms are involved in t cell mediated suppression?
Genes for color blindness and hemophilia are linked on the X-chromosome in humans with a recombination frequency of 30 %. A woman whose father was a color blind hemophiliac.
What percentage of the father's body was covered by burns? What percentage of the daughter's body received first-degree burns?
The genotype of F1 individuals in a tetrahybrid cross is AaBbCcDd. Assume independent assortment of these four genes, what are the probabilities that F2 offspring will have the following genotypes.
Blebbistatin is a newly identified small molecule inhibitor of myosin heavy chain. It binds to myosin-ADP-Pi complex with high affinity. What step of cross bridge function is affected?
Explain how promoter function was measured in the article "genetic analysis of the TBX1 gene promoter in ventricular septal defects" by Haihua wang, Dongfeng Chen, Liming Ma, Haihong Meng, Yumei Liu, Wne Xie, Shuchao Pang, and Bo Yan.
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