Principle of mendel to explain hereditary mechanisms

Assignment Help Other Subject

Reference no: EM131190961

1. State the three Principles of Mendel described to explain hereditary mechanisms. Also state one exception for each of the Principles.

2. Explain why genetic and physical maps of chromosomes are colinear.

3. If a is linked to b, and b to c, and c to d, does it follow that a recombination experiment would detect linkage between a and d? Explain.

4. In this question, assume that a set of 22 autosomal chromosomes has 20000 genes, X chromosome has 2000 genes and Y chromosome has 100 genes. We define 'relatedness' between two individuals (which are two gene sets) as:

relatedness = the number of genes in the intersection of two gene sets/the number of genes in the union of two gene sets

a) Calculate the relatedness between a mother and her son.

b) Calculate the relatedness between a mother and her daughter.

c) Calculate the relatedness between a father and his son.

d) Calculate the relatedness between a father and his daughter.

5. Spontaneous mutations can occur due to tautomeric shifts of bases. Describe this phenomenon and give one example of how a tautomeric shift can introduce a mutation.

6. (a) What are the genotypic differences between F^- cells, F⁺ cells, and Hfr cells? (b) What are the phenotypic differences? (c) By what mechanism are F^- cells converted to F⁺ cells? F⁺ cells to Hfr cells? Hfr cells to F⁺ cells?

7. Answer three of the following five questions about transposons.

a) What distinguishes IS and Tn3 elements in bacteria?

b) A researcher has found a new Tn5 element with the structure IS50L str^r ble^r kan^r IS50L. What is the most likely origin of this element?

c) What is the medical significance of bacterial transposons?

d) Explain how cut-paste transposons can increase their copy number (hence, replicate) in genomes.

e) Antibiotic resistance gene carrying plasmids can be transmitted between different bacterial species. Explain the evolution of plasmids from transposable elements.

8. In order to achieve genetic balance, organisms change the activity of their sex chromosomes. Give three mechanistic explanations on how this is achieved. Imagine that you are studying a new cell type. Suggest a set of experiments you would conduct to find out which of these mechanistic explanations is compatible with this cell type.

9. Explain why some tetraploids are fertile while some are sterile.

10. Genes a and b are 20 cM apart. An a+ b+/a+ b+ individual was mated with an a b/a b individual.

(a) Diagram the cross and show the gametes produced by each parent and the genotype of the F1.

(b) What gametes can the F1 produce, and in what proportions?

(d) Is this an example of the coupling or repulsion linkage phase?

(e) If the F1 were intercrossed, what offspring would be expected and in what proportions?

Reference no: EM131190961

Questions Cloud

Find the z-score : Find the z-score for which 99% of the distribution's area lies between -z and z.

Succession with replacement from a standard deck : Draw a tree diagram illustrating the events, two cards are drawn in succession with replacement from a standard deck of 52 and its suit is observed. How many total branches exist in this tree diagram?

Describe the history of the problem and why it is a problem : Describe the history of the problem and why it is a problem. Identify where and for whom it is a problem. Identify the purpose of your research on this problem.

Identify and confirm proper implementation of such analytics : How does one evaluate the types of tracking beacon variables passed to the analytics platform collection servers? How do tracking beacon audits help ensure reliable data collection?

Principle of mendel to explain hereditary mechanisms : State the three Principles of Mendel described to explain hereditary mechanisms. Also state one exception for each of the Principles. Explain why genetic and physical maps of chromosomes are colinear

Explain the ethical issues in marketing field : Explain the ethical issues in marketing field and identify and discuss about two companies in Australia who has been having some issues regarding the way they pursue their business.

Describe your selected educational psychologist : Explain how the learning theory is relevant to you as a future educator. In other words, how does the learning theory "look" in your future classroom? Provide at least two scenarios in the classroom to explain how you would apply the learning theo..

Could someone show me the process of creating a schema : Could someone show me the process of creating a schema, using the SQL Command Line, where the schema owner is DBSEC. In paticular how to create the DBSEC table in order to use the command "grant Select, Alter on DBSEC to DBSEC_ADMIN_ROLE". I am us..

User Account

All Pages