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Vinblastine is a pharmaceutical used to treat several cancers, such as lung and breast cancer and Hodgkin's lymphoma. It binds tubulin, a protein found in microtubules of the cytoskeleton, and prevents the proper formation of the mitotic spindle and the kinetochore. Cancer cell reproduce very rapidly, the drug is used to inhibit cell division in the cancer cells.
Considering this mechanism of action, do you predict that vinblastine would be an effective drug to treat a bacterial infection, since bacteria also reproduce rapidly? Provide a brief rationale for your prediction.
The DNA molecule is permitted to replicate in a solution containing all four unlabeled deoxyribonucleoside tripohosphates and deoxyadenosine triphospage that is labeled with 32P.
Compute the number of lipid molecules we added to each cell to make the tethered membrane.
Assume you are part of a team of scientists exploring a small, newly found island. This island is located approximately 150 miles off the coast of the mainland.
Cross a wildtype female with a yellow bodied male to generate an f1 offspring generation. Which allele is domonant and which is recessive. Justify your responce using your results.
Albinism in humans is inherited as a simple recessive trait. For the following families, estimate the gentypes of the parents and offspring.
List and explain at least three cellular features of bacteria that might be targeted to inhibit or kill a bacterial pathogen.
Draw the tripeptide His Glu Ala, with charges, at pH 5. Recognize the C-terminus, the N-terminus, a peptide bond.
Use the cleland representation create the reaction progress of thrombin, a serene protease using a ping pong mechanism on the hydrolysis of the substrate Ala-Arg-Gly-Ala
Which declaration is NOT true about DNA replication. Replication can only begin at distinct regions known as origins of replication.
A patient with hypothyroidism presents with low T3 and T4, and elevated TSH & antibodies to thyroglobulin. The thyroid is infiltrated with lymphocytes that have replaced large part of thyroid.
Assume if you take a mature prokaryotic mRNA, and use reverse transcription to create DNA from it, will it resemble the original DNA sequence?
What are the genotypes of parent orange-fruited plants. Within the two groups defined by bone mass smaller skeletons have bones with evidence of epiphyseal plates should be. Give the age group and gender of the individuals in this fine.
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