Reference no: EM132383542

There are three amino acids that are part of a polypeptide chain.

Aspartic Acid, Cysteine and Lyseine.

A mutation happens that results in

Aspartic Acid, Valine and Lyseine.

Which of the following is true regarding how the overall protein impacted by this change/mutation? Please confirm answer 1 below is correct.

1 - The R group of the new amino acid valine has different chemical properties than the R group of the cysteine. The protein will therefore mis-fold and not function correctly

2- The new amino acid valine has replaced Cysteine. But, since the number of amino acids is the same, there will be no change in the three dimensional or folding or function of the protein

3 - Since this is a linear section, it does not influence protein folding. As a result there will not be a change in the protein structure or its function

4 - The charges will balance and the protein will fold as usual. The charges are the same because the new amino acid is bound on one side by with a negatively charged amino acid and the other side by a positive charged R group, thus balancing.