Nucleotide-excision repair differ from base-excision repair

Reference no: EM13533517

How does nucleotide-excision repair differ from base-excision repair?

Nucleotide-excision repair reverses the chemical reaction that caused the lesion, whereas base-excision repair removes thedamaged bases and replaces them with normal ones.

Only the base isremoved in base-excision repair, whereas the entire nucleotide isremoved in nucleotide-excision repair.

Base-excisionrepair requires no protein components and can occur by simpleabsorption of UV light, whereas nucleotide-excision repair requires several enzymes.

Base-excisionrepair recognizes and removes single damaged bases, whereasnucleotide-excision repair is more general, recognizing many different kinds of lesions that distort the DNA molecule.

Reference no: EM13533517

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