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Question: A patient has been brought to you who is thought to have a mutation of the DVL1 gene, a human homologue of the Drosophila Disheveled gene. The hypothesis is that this mutation eliminates the ability of the DVL1 protein to bind to the human equivalent of Axin in one tissue. What effect would you predict this mutation has on transcription of the target genes in this tissue? Describe your answer to receive full credit.
What is basics of epidemiology, brief description on Understanding basics of epidemiology
Trace path from the femoral vein in a healthy female to the lower lobe of the right lung via the right pulmonary artery. Explain all major structures on the way.
If succinate is used as the electron donor in oxidative phosphorylation, how many ATPs should be generated for each pair of electrons donated by succinate. explain What does UNCOUPLING mean.
Explain two ways that mutations can affect the phenotypes that does not include alteration of the protein coding sequence.
Both endocrine and nervous system are major regulating system of the body; but nervous system has been compared to an airmail delivery system and the endocrine to pony express. Briefly explain the comparison.
A person is heterozygous for a mutation in a STAT gene replaces a tyrosine in coding sequence with a phenylalanine. The missing tyrosine is normally phosphorylated by a JAK bound to a cytokine receptor.
Discuss the five main types of histone proteins, and describe what role each of them plays in the nucleosome. Based on what you know about them,
A woman from the family with normal cholesterol marries a man with no LDL receptors, and all their children have cholesterol levels twice the normal of the mother.
Suppose you add five micrograms of purified acid phosphatase to the pur acid phosphatase reaction - compute the amount of acid phosphatase in 400 microliters of wheat germ extract
Explain how adult stem cells can sense and respond to the nutritional status of an animal. Explain what kind of cues an adult stem cell can respond to, and where these cues are coming from.
Explain two processes that ensure that your full future sibling is going to be genetically different from you even though you have the same parents.
In 1997, the magazine Public Interest published an article entitled IQ and economic success in which can be discovered the given table relating IQ to earnings
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