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Question: Most human obesity does not follow Mendelian inheritance patterns, because body fat content is determined by a number of interacting genetic and environmental variables. Insights into how specific genes function to regulate body fat content have come from studies of mutant, obese mice. In one mutant strain, tubby (tub), obesity is inherited as a recessive trait. A comparison of the DNA sequence of the tub+ (wild-type allele, or the nonmutated allele) and tub alleles has revealed a single base-pair change: within the transcribed region, a 5' G-C base paur has been mutated to a T-A base pair. The mutation causes an alteration of the initial 5' base of the first intron. Therefore in the homozygous tub/tub mutant, a longer transcript is found. Propose a molecular based explanation for how a single base changes causes a nonfunctional gene product to be product, why a longer transcript is found in the tub/tub mutants.
Describe the four tissue types, nervous, muscle, epithelial, connective. How did tissues and multicellular animals evolve? How do animals develop.
The information to the below were collected for the bovine carbonic anhydrase-catalyzed reaction described by, Use these values to determine the value of KM,
Specify the potential confounders that have been recognised by the authors? Explain how have they dealt with them at the design stage and at the time of analysis?
The client tells nurse that he does not understand what that means. How would nurse explain this in terms the client would understand.
Was the hypothesis supported and What is your conclusion
Using examples, discuss types of genetic mutations that result in faulty proteins and disease,
The seeds in bush bean pods are each the item of an independent fertilization event. Green seed color is dominant to white seed color in bush beans.
Should society subject pregnant women to dietary restrictions during pregnancy to protect the fetus from the effect of defective genes they carry.
In bacterium that possesses antibiotic resistance and potential to persist through very adverse conditions, such as freezing, drying, or high temperatures, DNA have to be located within, or be part of, which structures.
It is a very curcial concept to understand how the immune response is mounted against viruses, bacteria, protozoans and helminthes. For an effective immune response, both innate and adaptive immunity should work together.
A chemical reaction in which polymers are synthesized from their building blocks is called.
Oxygen is the final electron acceptor of this pathway. Glycolysis is the only energy yielding step of this pathway.
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