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Place these steps of the insulin signaling pathway in the correct order from insultin is secreted to glucose enters the cell. Place all eight steps. The abbreviation PIP2 is used for phosphatidylinositol 4,5-bisphosphate; PIP3 is used for phosphatidylinositol 3,4,5-trisphosphate.
1. Activation of Akt
2. Binding of insulin to the alpha subunit of the insulin receptor
3. Phosphorylation of IRS proteins
4. Conversion of PIP2 to PIP3
5. Glut4 receptors transported to cell membrane
6. Phosphorylation of phosphinositide 3-kinase (PI-3K)
7. Activation of PIP3-dependent protein kinase B (PDK1)
8. Activation of insulin receptor tyrosine kinase
Perform a BLAST search and a result has an E value of about 1 x 10-4. What does this E value mean? What are some parameters on which an E value depends?
Why water is known as polar solvent? How is hydrogen bonding involved in cohesive attraction of water molecules? Water molecules also attract other sorts of molecules, particulary ions.Why is this.
A man drops a baseball off of the top of the Empire State Building. If the action force is the pull of the Earth on the ball, then what is the reaction force. What is the most possible diagnosis of the condition described? Explain.
Name the 3 types of chromosomes found in human cells based on the location of the centromere.
Specify the patient’s role in alteration of the behavior? What research has been done in order to substantiate effect of the patient’s involvement? What is measured?
What could be the base sequence of the RNA after transcription happens? Explain the importance of first and last codons? Specify the meaning do these codons have for the protein synthesis?
define how the axonal membrane potential is restored. Describe how resting ionic distributions are maintained.
Re-examine the timeline of the laboratory medicine history and discoveries. Post and discuss one discovery/issue incident which you feel moved the laboratory profession forward in greatly assisting cliniciana.
Unlike bilaterally symmetrical animals, radically symmetrical animals are almost never able to move themselves from place to place.
In many countries, conservationists are trying to design national park systems so that "islands" of natural area (the big parks) are connected by thin "corridors" of undisturbed habitat. The idea is that this arrangement will allow animals and plants..
Discuss the properties of the wild type amino acid? Properties include charge, shape, size and flexibility, features unique to the amino acid.
Determine which variable is the independent variable--the variable that was controlled by the researchers? Is the independent variable on the x -axis or the y -axis?
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