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Imagine you have engineered a set of genes, each encoding a protein with a pair of conflicting signal sequences that specify different compartments. If the genes were expressed in a cell, predict which signal would win out for the following combinations. Explain your reasoning.
(a) Signals for import into the nucleus and import into the ER(b) Signals for import into peroxisomes and import into the ER(c) Signals for import into mitochondria and retention in ER(ie, the KDEL signal for retrieval from Golgi to ER). (In this case, you are to assume that we have specially engineered the protein to have a KDEL sequence, and a mitochondrial import sequence, but no amino-terminal signal sequence.)
The global community is plagued by increasing incidence of lung cancer, colorectal cancer, breast and pancreatic cancers, prostate cancer, non Hodgkin lymphoma, liver, ovarian and esophageal cancers.
Assume you have 2 tubes containing cultures of genetically distinct bacterial strains. You know that when you mix the two together, you get Horizontal gene transfer.
What specific DNA sequence would you look for to determine if your mouse has the knockout gene, and what techniques would you use to detect this DNA sequence?
Henri tested the effects of a blood pressure reducing drug and found that blood pressure dropped significantly in those treated but did not change in an untreated control group. What is a reasonable conclusion from this experiment?
Discuss in three sentences or less why DNA polymerases alone cannot initiate complementary strand formations.
Animals obtain energy during a sequence of chemical reaction in which sugar (C6H12O6) and oxygen gas (O2) are reactants. This process produces water (H2O) and carbon dioxide (CO2) as waste products. How might you use radioactive isotope to find out w..
Jimmy, a new undergraduate researcher in the lab, is told to make a vector having a copy of the CELLBIO gene from Dr. Acosta's genome as well as a selectable gene, Ampr.
Assume you are studying a microorganism from a hot spring that uses organic carbon as an energy and carbon source.
An arginine residue in the matrix side proton channel of a subunit of ATP synthase is near the aspartate residue in the c ring subunit.
What are the major adaptations of amphibians, birds, reptiles and mammals? What are the dissimilar types of animals in these groups? Anmiotic egg,plastron, carapace, snake, lizard, turtle, feathers How did jaws evolve.
The human body produces a variety of immunoglobulins. Explain why does the body need so many different classes and subclasses of these immunoglobulins?
What is the major morphological difference between mammalian red blood cells and avian red blood cells? Describe what is happening in plasmolysis when onion cells are placed in a hypertonic solution. Sketch a plasmolysed cell.
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