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Suppose you are studying two mutant strains of E. coli that are deficient in DNA replication. One mutant strain is known to have no DNA ligase and the other mutant strain is known to have no DNA polymerase I, but in both cases the other enzymes involved in DNA replication are normal. The DNA synthesized on the "LAGGING STRAND" from both mutants is found to be largely similar in characteristics, but there is also a difference in their characteristics when the two strains are compared. How would you expect the lagging strand DNA from the two mutant strains to be similar and how would they differ from each other?
Discuss how is cancer different from most other types of genetic diseases? Outline Knudson's multistage theory of cancer and explain how it helps to unilateral and bilateral cases of retinoblastoma.
Distinguish between a hereditary germline cancer, such as those caused by BRCA1 mutations, and cancers that result from two somatic mutations in the same gene in the same cell.
Which of the following statements about eukaryotic RNA is TRUE?
In the telophase stage of mitosis, microtubules gather along the cell's equator. The purpose of these microtubules is to what.
Some vertebrate animals lack marrow cavities in many bones. Using your knowledge of bone structure, predict in which of the following you would expect to find the most evidence of solid bones.
The fact that some pure solutions of hydrocarbons do not readily evaporate at room temperature is a result of- Select one:
Vitamin D resistant rickets is usually an X-linked dominant situation. The disease is caused by mutations the PHEX gene and results in bone deformity and bow leggedness.
In 1918, the tsar and tsarina of Russia and their five children were presumably assassinated and buried in an unmarked grave. Later, several women came forward and claimed that they were in fact Anastasia.
Both endocrine and nervous systems are major regulating system of the body; though, nervous system has been compared to an airmail delivery system and the endocrine system to the pony express. In brief explain this comparison.
Examine the nature of water and how its unique chemical properties impact water regulations in plants. Elucidate the structure and function of the leaf to water regulation.
Two pros and two cons of GM food. From those pros and cons, do you think GM foods are safe to eat? Why or why not.
If humans and shrews shared the common ancestor roughly 80 million years ago, ignoring multiple substitutions at the same site, how several amino acid differences have to be expecting to see between a human and shrew Fibrinogen B sequence.
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