How would call base substitution in the coding dna sequence

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Reference no: EM133290153

Assignment:

1. What is true for ribosomes (only one correct answer)

a) Prokaryotes does not have ribosomes

b) All ribosomes consists of small and big subunit

c) Ribosomes contain non-coding DNA

d) 80S is prokaryotic ribosome

2. A region of DNA which is highly methylated is called (only one correct answer):

a) hypomethylated

b) hypermethylated

c) pseudomethylated

d) bimethylated

3. In the case of sickle cell anaemia in the beta-globin chain there is amino acid Glu changed to Val. How would you call base substitution in the coding DNA sequence (only one correct answer)?

a) Silent

b) Nonsense

c) Missense

d) Nucleotide mismatch

4. Translation start codon for mRNA molecule is (only one correct answer):

a) ATC

b) TAG

c) AUG

d) TCG

5. Somatic mosaicism most often is caused by mistake in (only one correct answer):

a) Postzygotic mitotic cell division

b) Gametogenesis

c) Meiotic division I or meiotic division II

d) In meiotic division of zygote

6. Correct folding of proteins is mediated by (only one correct answer):

a) Aminoacyl-synthetase

b) Chaperons

c) Spliceosomes

d) Proteinases

7. Which statement about DNA methylation of a gene's CpG islands in the promoter region is correct (only one correct answer):

a) It degrades the gene's mRNA

b) It splits the gene

c) It represses gene expression

d) It promotes gene expression

8. Eukaryotic post-transcriptional modifications occurs in (only one correct answer):

a) Cytoplasm

b) Nucleus

c) Ribosomes

d) Endoplasmic reticulum

9) The process of generating different proteins from the one transcript is called (only one correct answer):

a) Splicing

b) Diversification

c) Alternative splicing

d) Transcription

10) In the case of triploidy the karyotype is (only one correct answer):

a) 2n+3

b) 2n-1

c) 3n

d) 2n-3

11. The interphase of eukaryotic cell does not include (only one correct answer)

a) G1

b) S

c) G2

d) M

12. Which of the following is not an epigenetic maintainer?

a) Non-coding RNA

b) DNA modifying enzymes

c) Histone modifying enzymes

d) Histone variants

13. What is true about cyclins and CDK (only one correct answer):

a) Concentration of cyclins are stable through the cell cycle

b) CDK are activated by forming a complex with cyclins

c) Concentration of CDKs is inconsistent through the cell cycle

d) Cyclins are not involved in the cell cycle regulation

14. Assembled ribosome contains (only one correct answer):

a) DNA and RNA

b) Proteins and RNA

c) tRNA and proteins

d) Amino acids and RNA

15. In cytokinesis (only one correct answer):

a) DNA replication takes place

b) Duplication of organelles

c) Division of cytoplasm and organelles

d) Division of the nucleus

16. Translation initiation codon AUG is sequence of:

a) DNA molecule

b) mRNA molecule

c) tRNA molecule

d) Ribosome

17. Mechanism of interaction of short interfering RNAs on regulation of gene expression involves (only one correct answer):

a) Degradation of mRNA

b) Degradation of proteins

c) Degradation of DNA

d) Degradation of piRNA

18. Homologous recombination takes place in (only one correct answer):

a) Prophase I

b) Metaphase I

c) Prophase II

d) Metaphase II

19. Which protein is important for lining up sister chromatids in metaphase chromosome (only one correct answer:

a) Kinetochore

b) Condensin

c) Histones

d) Cohesin

20. Amyloid is:

a) Soluble protein

b) Protein aggregates

c) Amino acid

d) Disease

Reference no: EM133290153

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