How is the feedback disrupted by diabetes

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Assignment:

Diabetes is a disease resulting from elevated glucose levels in the bloodstream due to a disrupted feedback loop. In healthy individuals, the pancreas maintains the set point for blood glucose levels by secreting the hormone insulin. Following a meal, digestion and absorption result in elevated glucose levels in the blood. Elevated glucose levels are detected by pancreatic beta cells which then release insulin stored within vesicles of the beta cells. The secreted insulin enters the bloodstream and facilitates the transport of glucose into cells of the body where it is stored or used as energy for cellular work.

Apply your knowledge of homeostatic pathways to classify the feedback loop as positive or negative. How is the feedback disrupted by diabetes? Explain your answer by referencing the roles of pancreatic beta cells within the homeostatic pathway.

Reference no: EM133369120

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