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An elderly man, Tom, complained to his doctor about intense pain in the joint area of his big toe. The pain would last several days, subside, and then recur weeks later. Tom's blood work revealed a very high uric acid concentration (well above the 7.4 mg / dl upper limit). What is this condition commonly called? Give an underlying cause for uric acid buildup in the plasma. How is elevated uric acid associated with the pain that Tom experienced?
An A=T mispairing leads to an A=C substitution. The other DNA helix will contain a(n) __ pair.
A 55-year old woman presents with symmetric stiffness and swelling of the proximal interphalangeal joints of the hands and of the metacarpopharyngeal joints, as well as fatigue, malaise, and myalgia. Symptoms are worse in the morning or after exte..
The gene that encodes a human's ability to differentiate red/green colors is X-linked. A mutant allele of this gene results in red/green colorblindness, and it is recessive to the wild-type version.
Suggest two different strategies for synthesizing a 0.5-kb gene. Discuss the advantages and disadvantages of both methods.
Determine what is the most common mechanism for repairing damage to DNA? Individuals with xeroderma pigmentosum inherit a faulty DNA repair mechanism.
Suppose that you perform the following monohybrid cross in dogs: Aa X Aa, in which the dominant A allele produces black coat color and the recessive a allele produces a white coat color.
Why is it beneficial to plants that soil particles have negatively charged surfaces.
You are ready to run your gel but you discover that there is no more running buffer. You need to make 400 ml of 1X TBE containing 0.5 ug/ml ethidium bromide. The stock solution of ethidium bromide is at a concentration of 10 mg/ml. How much of the..
A diploid cell contains three pairs of homologous chromosomes designated C1 and C2, M1 and M2, and S1 and S2. No crossing over occurs.
Very often organism's traits are caused by a combination of its genes and its environment. Which environmental factors cause genetically formed bacteria to turn green?
A heterozygous bald, color-blind man marries a non-bald woman with normal vision, whose father was non-bald and colorblind and whose mother was bald with normal vision. List the phenotypic expectations for their children.
Discuss different models for DNA replication that were considered by early researchers. Describe why they settled on the current model for DNA replication.
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