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The effect of the drug fluoxetine (Prozac) on isolated rat brain mitochondria was examined by measuring the rate of electron transport (units not given) in the presence of various combinations of substrates and inhibitors .(a) How do pyruvate and malate serve as substrates for electron transport?
(b) What is the effect of fluoxetine on electron transport? Explain.
(c) Fluoxetine can also inhibit ATP synthase. Why might long-term use of fluoxetine be a concern?
Give two mechanisms that allow the nerve cell to recover from the effects of an action potentials and neurotransmitter release.Say how the mechanisms cause the cell to recover.
Choose two organelles and compare them relative to structure and function. Describe what would be the specific probable effects on the cell if each of these organelles were lost.
How does the homeostatic mechanism regulate osmolarity or solute concentration of the blood in response to a meal high in salt?
What are the structural components of biological membranes and their functions? Find out the most probable pathways or mechanisms by which molecules such as CO2, H20, CO, NH3, cholesterol, Na+, amino acids, DNA and H+ will cross the membranes?
How and when do the molecules produced by adipocytes result in adverse consequences which are associated with obesity?
What would the cardia output be of a patient with a blood pressure of 120/75, a pulse rate of 40 beats/minute, a stroke volume of 70mL/beat, and a respiratory rate of 25 breaths a minute?
Which statement about multiple locus probes is INCORRECT.
What is the disorder beriberi and how is this relevant to pyruvate dehydrogenase mechanism? and why does its exposure to arsenite or mercury lead to symptons similar to beriberi.
Activation of metabotropic glutamate receptors in neurons is often coupled to the activation of phospolipase C PLC.
Two genome-wide association studies sought genes that contribute to intelligence. The first considered 1000 Mexican-American participants in the San Antonio Family Heart study, and found evidence pointing to genes on chromosomes 3,6 and 18.
There are forty chromosomes in somatic cells of the house mouse. how many chromosomes does a mouse receive from its father and how many autosomes are present in a mouse gamete?
Tongue rolling is dominant to non-rolling and PTC tasting is dominant to non-tasting. Show the cross between two individuals who are heterozygous for both traits. Give the phenotypic ratio of offspring.
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