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Q1. A patient who inherited two defective copies of a gene essential by white blood cells, suffered from a severe immune deficiency disease. The patient recovered from a disease following gene therapy, in that he received an expressed copy of the 'missing' gene (the desired outcome). Unfortunately, he afterwards developed leukaemia, a cancer involving the white blood cells (an unexpected outcome). The introduced gene was not responsible as it did not encode a carcinogen or a regulator of cell replication.
In a few sentences describe how the transformation might or DNA integration process has caused this outcome?
Q2. Autoimmune haemolytic anaemia is caused in general by auto anti bodies of the IgG and IgM classes. Can antibodies of other classes such as IgA, IgD, IgE cause autoimmune haemolytic anaemia?
You get a soil sample and run an enrichment culture on it. You give the organisms in the culture with all of the ingredients required for growth except for nitrogen. What result do you expect to have at the end of the experiment.
On the Pacific island of Guam, large herbivorous bats called "flying foxes" commonly feed on cycad seeds, a potent source of neurotoxins. The flying foxes do not visit male cones. As a result, what should be true.
Compute the change in energy of an atom that emits a photon of wavelength 2.21 meters. (Planck's constant is 6.626 x 10-34 joule seconds; the speed of light is 2.998 x 108 m/s)
Explain how you would build a Windkessel machine, including individual parts and assembly. How would you operate this machine? What cardiovascular physiology principle would machine display and how would you measure this phenomenon.
If the mutation is in mitochrondrial DNA, will the four haploid cells probably be all Pyr-, all Pyr+, or a combination? What if the mutation is in nuclear DNA. Why is mitochondrial function critical for growing on pyruvate.
Briefly explain why this mating produces a triploid individual. Why can mitosis proceed normally in triploid cells, but meiosis cannot.
What are the benefits of genetic engineering versus the potential risks. Critics claimed that the experiment was inconclusive. Which of the criticisms would be addressed by using a swan-necked flask in its place of the unsealed flask.
What techniques might be used to characterize the structure and composition of the structure. Which of the follow will the nurse include in her teaching plan for this patient.
Your friend has now joined a lab that studies vesicle budding from the Golgi and has been given a cell line that does not form mature vesicles. He wants to begin designing some experiments but wasn't listening carefully when he was told about the mol..
Evaluate and contrast the major muscle groups of the upper and lower limbs and relate their similarities and differences to their function.
If a cube representing the cell is 5um on a side, compute the surface area to volume ratio, and explain why this is or is not a good size for a cell.
Which condition is best described while the ovaries shut down their production of eggs and hormones like estrogens and progesterone approximately 30 years after they started.
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