Histidine biosynthesis in escherichia coli

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Several genes code for enzymes that are responsible for histidine biosynthesis in Escherichia coli. Part of the amino acid sequence for one of these enzymes is :

AUG CCU UGG GCC CAA AAA UGC

A series of mutants that have lost activity for this enzyme are recovered. The mutant products that analyzed and found to have the following amino acid sequences:

Mutant 1: Met-Pro-Trp-Pro-Glu-Lys-Cys

Mutant 2:Met-Pro

Mutant 3:Met-Pro-Cys-Gly-Pro-Lys-Met

Mutant 4:Met-Pro-Trp-Pro-Lys-Asp

Choose the correct type of mutant that occurred in the DNA to produce each mutant type.

Nonsense___

Point ___

Addition ___

Deletion ___

A. Mutant 1
B. Mutant 2
C. Mutant 3
D. Mutant 4

Reference no: EM132818390

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