Genetic and epigenetic changes of cancer.

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For each of following, explain one genetic and one epigenetic change which could lead to cancer. Select a specific gene and a specific alteration. Explain the effects of the modifications and why it might contribute to the cancer. 

Every genetic or epigenetic modifications must be:

a and b. modifications to a gene encoding a protein involved in apoptosis

c and d. modifications to a gene encoding a DNA damage repair protein

e and f. modifications to a gene encoding involved in cell cycle regulation.

Reference no: EM1312380

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