Finding lod score for association in chromosomal location

Assignment Help Biology
Reference no: EM1398027

Parkinson disease (PD) is a neurodegenerative disease that has been associated with a significant number of different genes, therefore showing it to be genetically heterogenic. One recent study in 278 families found evidence of two such possible loci. Evidence for linkage to chromosome 18q11 was presented by Gao et al. in 2009. Which of the following would be considered reputable evidence for this?

A. finding the Lod score for association between the chromosomal location and PD to be 4.1
B. finding the locus to be in Hardy-Weinberg equilibrium in the population
C. lack of quantitative difference for the occurrence of both in individuals
D. analysis of all other possible SNPs with no such association to chromosome 18
E. use of persons from multiple ethnic and geographic backgrounds in the study

 

Reference no: EM1398027

Questions Cloud

Mean net weight of packages of ground chuck : A state meat inspector in lowa has been given the assignment of estimating the mean net weight of packages of ground chuck labeled " 3 pounds." Of course, he realizes that the weights cannot be precisely 3 pounds.
Calculate the amount of atp equivalents : Calculate the amount of ATP equivalents produced by total catabolism of adenosine compare this with ATP equivalents produced by total catabolism glycine.
What is the molarity of the drug in he petri plates : What is the molarity of the drug in he Petri plates?
Two way anova with interaction in statdisk : Set up the following null and alternative hypotheses for both factors and their interaction. You should have three verbal statements, not symbolized statements.
Finding lod score for association in chromosomal location : Parkinson disease (PD) is a neurodegenerative disease that has been associated with a significant number of different genes, therefore showing it to be genetically heterogenic.
Family spending per year on dental expenses : The Human Relations Department of Electronics Inc. would like to include a dental plan as part of the benefits package. The question is: How much does a typical employee and his or her family spend per year on dental expenses?
Example of repeated measures analysis of variance : Give an example of a repeated measures analysis of variance (ANOVA)--no examples of therapy or temperature.
Calculate the total transportation cost : Compute the total "load-distance" LD score for the current solution, and then try to find an improved layout and calculate the total transportation cost.
Is chromatography a valid method : Is chromatography a valid method for identifying amino acids from an unknown mixture like serum? Wht or why not.

Reviews

Write a Review

Biology Questions & Answers

  Genetics concepts

Explain how many kinetochores are there within the human cell at mitosis? Surprise, your boss has invited himself or herself to dinner! All you have is some wilted, day old lettuce.

  Find the expected population size

Provided the total population size of the population in Table 2 (in year 2012), using the per capita growth rate in question five, and assuming that this growth rate does not change,

  Demonstrate their brain quality to potential mates

When a tropical moth is touched on the thorax it lifts its forewings up abruptly, exposing its brightly coloured hind-wings. What causes the moth to behave this way? What significance can we attach to the fact that the verbal ability scores of ado..

  Discuss the types of drugs

Discuss the types of drugs which might be expected to be ordered for the patient with a localized infection such as an infected vaginal laceration.

  Discuss different models for dna replication

Discuss different models for DNA replication that were considered by early researchers. Describe why they settled on the current model for DNA replication.

  Why is stamina inversely associated to work load

Who is the story about? What is he or she trying to do. What happens while he or she tries to do it? What happens in the end.

  Pre mrna processing

What procedure ensures that pre-mRNA processing is co-transcriptional? Disucss ow are all three steps of processing sequentially controlled?

  C value paradox

An amphibian that lives in a swamp has thirty fold more DNA than a human who lives on the forty-eight floor of luxury apartment apartment complex.

  Which would show that the two populations are different

A storm brings two formerly separated populations of beetles together. They look very similar. Under the biological species concept, which would show that the two populations are different species.

  What sort of mutation the insertion of the adenine

Analyze the stressors employees might experience as a result of the underperforming economy and current retraction of business, and make at least three recommendations for how approximately any leader or manager might help mitigate those stressors. S..

  Which of statements regarding cellular respiration is false

Which of the statements regarding cellular respiration and photosynthesis is false? Select one: Cellular respiration and photosynthesis are chemically reverse reactions, but they use different pathways.

  Estimate the cotransduction frequency for pur and nad

In a generalized transduction system using P1 phage, the done is pur+ nad + pdx- and the recipient is pur- nad- pdx+. The donor allele pur+ is initially selected after transduction.

Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd