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Q. You are working in a human genetics laboratory that studies causes and treatments for eye cataracts in newborns. This disease is thought to be caused by a deficiency in an enzyme called galactokinase, but the human gene that encodes this enzyme has not yet been identified. At a talk by a visiting scientist, you learn about a strain of bakers' yeast that contains a mutation called gal1- in its galactokinase gene. Because this gene is needed to metabolize galactose, the mutant strain cannot grow in galactose medium. Knowing that all living things evolved from a common ancestor and that distantly related organisms often have homologous genes that perform similar functions, you wonder if the human galactokinase gene can function in yeast. Because you have an optimistic temperament, you decide to pursue this line of experimentation. You isolate mRNA gene transcripts from human cells, use reverse transcriptase to make complementary DNA (cDNA) copies of the mRNA molecules, and ligate the cDNAs into circular plasmid DNA molecules that can be stably propagated in yeast cells. You then transform the pool of plasmids into gal1- (gal1 minus) yeast cells so that each cell receives a single plasmid. What do you think will happen when you spread the plasmidcontaining cells on Petri plates that contain galactose as a carbon source? How could this approach help you find the human gene encoding galactokinase?
What everyday tasks do you think would become more challenging if Homo sapiens were full- time quadrupeds in the place of full-time bipeds? Explain the answers in details.
What aspects of social and work environment in a college cafeteria will be of particular interest to a sociologist since of his or her sociological imagination.
Which term describes tonicity of the external solution. Were latitude the only control of temperature, the isotherms would run straight across the map from east to west. Describe one region of the world where this hypothetical isotherm pattern is rea..
Why or why not explain with reason? Work the genetics problem predicting the frequencies of the versions of this trait among their prospective children.
Is this an instance of a positive or negative feedback mechanisms? What is the initial stimulus? What is the result.
Do you think that using recombinant DNA technologies to change the genetic composition of human egg cell is ever justified? If so, what restrictions have to be placed on such a use.
Approximate the broad-sense heritability for seed number in this population. In a natural population of out breeding plants, the variation of the total number of seeds per plant is 16.
How would you answer to a person who argued that there is nothing to worry about because natural systems, through natural succession, will heal the wounds of human activities and restore the balance of nature.
Imagine looking during a microscope at a squashed onion root tip. The chromosomes of many of cells are plainly visible. In some cells, replicated chromosomes are aligned along center (equator) of the cell. These particular cells are in which stage of..
Design a biotechnological approach to getting better the amino acid content of wheat. How are you going to communicate your decision to the surgeons, medical center employees, governing board, and to public.
What are the genotypes of parent orange-fruited plants. Within the two groups defined by bone mass smaller skeletons have bones with evidence of epiphyseal plates should be. Give the age group and gender of the individuals in this fine.
What would be TRC for a male with the genotype AABbCcDD? For a female. In contrast, each dominant allele in an individual's genotype contributes 12 ridges to the TRC in males and 10 ridges to the TRC in females.
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