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The ß-hemoglobin locus in humans is implicated in resistance to falciparum malaria. Estimates of fitness vary geographically, but suppose that, in one particular area with endemic malaria, the relative fitnesses of genotypes involving the alleles A ("normal"), S (sickle) and C are:
genotype AA SS CC AS AC SC
rel fit 0.82 0.15 1.20 1.00 0.82 0.55
If in the population the frequencies of the three alleles are (i) pA=0.9000, pS=0.0500 and pC=0.0500 or (ii) pA=0.6000, pS=0.2000 and pC=0.2000, what would be the frequencies in the next generation? (Assume that the generations are separate and maintain 4 decimal places throughout your calculation). What do these results suggest about the final outcome of selection given these two different starting conditions (i and ii)?
If the genes were expressed in the cell, predict that signal would win out for the following combinations. Give details your reasoning.
How could you explain the occurrence of birth defects (caused by altered genes) in children and grandchildren of WWII atomic bomb victims, while the victims themselves were only mildly affected.
Explain the cells you were able to see in the blood smear. Are they different than bacterial cells you have observed.What is the reason of immersion oil?
What is the possibility that their next child will show both defects? Demonstrate the work.
He was puzzled, combative, and he refuses to drink any water or any liquid. He lived on Oct. 7th, 1849. While said to the man's name, the student thought "Nevermore!" What was his diagnosis.
Sickle cell anemia is a disease of red blood cells in which the genetic mutation in DNA leads to a mutation in hemoglobin. A single base vary alters the DNA sequence CTC to CAC which codes for the wrong amino acid. What amino acid is coded for throug..
Organize the genotype in the table, define the origin (parental, single cross-over progeny and double-crossover progeny) and find out the order of the genes on the chromosome.
define the results of the three chi-squared analyses. what do these analyses tell you about the chromosomal arrangements and the genotypes of plants 1 and 2 and the events that occured during gamete production.
In a separate piece of paper, make a simple family tree for a couple showing children, and lineages from two children showing grand children, great grandchildren, great great grandchildren, and great great great grandchildren.
Hydrogen peroxide (h2o2) breaks down into water and oxygen. Explain why this is a chemical reaction. What are reactants and products in the reaction.
Your uncle promises to give you $550 per quarter for the next five years starting today. How much is his promise worth right now if the interest rate is 8 percent compounded quarterly.
If you obtain an RF value of 45 percent in one experiment, what can you say about linkage? (The actual figures are 58, 52, 47, and 43 out of 200 progeny)
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