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In humans, nearsightedness and phenylketonuria are both inherited as single-locus autosomal recessive traits that assort independently. Assume that a family has been identified in which both parents were phenotypically normal, but their first child was phenylketonuric and their second child developed nearsightedness.
a. What is the probability that their next child will show both defects? Show your work.
b. What is the probability that their next child will exhibit neither defect? Show your work.
A calorie is the amount of heat required to raise the temp of one gram of water by 1°C (1 cal = 4 J). A marine iguana from the Galapagos Islands weighs about two kg.
Carbonic anhydrase has a molecular weight of 30,000g/mol and a turnover of about 1 million per second. If you are given a solution saturated with CO2 containing 2 micrograms (ug) of carbonic anhydrase.
Which precautions would you follow to preserve Bacillus subtilis and what are the physical and chemical hazards of handling Bacillus subtilis?
Two NotI restriction enzymes cleave DNA on opposite sides of the Dbm gene in a species of yeast. A molecular probe for Dbm detects a DNA restriction fragment of 8.5 kb in organisms that are wild type at Dbm.
The urine of a thirteen year old boy turned dark brown several weeks after a bout with strep throat. The diagnosis was glomerulonephritis.
lex A is an E. coli gene whose product regulates the transcription of certain target genes that are located at different positions in the bacterial chromosome.
Determine which of the following repair pathways do not involve the use of a homology dependent repair system?
Having studied the usefulness of restriction enzymes and the process of molecular cloning, propose a use for these two genetic technologies.
Discuss why is even weak selection still stronger than drift in very large populations at non-neutral loci?
Describe one growth factor and one mitogen and the cellular signaling they trigger within the cell, as well as the final result of that signaling. What are carcinogens and why and how might they effect the cell cycle in the transformation of normal ..
Explain the possible fates of DNA that in brought into the recipient cell during generalized transduction.
What veins are most likely involved? What pathologic changes have happened in these veins, and what is the most probable cause in this patient's case.
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