Find probability that the child be phenotypically abnormal

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A married couple seeks your advice after having a child affected by an autosomal dominant condition. Studies reveal they are both heterozygous carriers of the mutation but are phenotypically normal. The disorder has an 80% penetrance in all affected individuals. They are considering having a second child. What is the probability this child with be phenotypically abnormal (express the disease)

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33%
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80%

 

Reference no: EM1398111

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