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Explanation of how overexpression

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Glioblastoma multiforme is a highly malignant form of brain cancer. MicroRNA-21 (miR-21) is overexpressed 100-fold in glioblastoma compared to normal cells. Choose from below the most correct explanation of how overexpression of a microRNA could lead to malignancy.
b. miR-21 suppresses translation of tumor suppressor mRNA.
c. miR-21 activates translation of a cellular maintenance mRNA.
d. miR-21 activates translation of tumor suppressor mRNA.

Reference no: EM131051915

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