Explain the rationale for dynamic function tests

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Reference no: EM133897798 , Length: word count:4000

Investigation of Adrenal Disease

All questions below are mandatory.

Question 1. Discuss the biochemistry and physiology of the adrenal cortex and medulla. Include their normal functions. 400 words

Question 2. Explain the synthesis, control, function and metabolism of aldosterone, cortisol, ACTH and catecholamines. 600 words

Question 3. What changes would you expect in aldosterone, cortisol, ACTH and catecholamine results for a patient suffering from the following conditions:300 words
• Cushing's Syndrome
• Conn's Syndrome
• Addison's disease
• Phaeochromocytoma.

Question 4. How would adrenal dysfunction effect the electrolyte balance? 300 words

Question 5. Explain the rationale for dynamic function tests for the assessment of adrenal disorders. 300 words

Question 6. Which tests are relevant for investigating adrenal disorders? Hint(Short Synacthen Testand Dexamethasone suppression Test)How is it performed? Get Assignment Help from the Best tutors!
Describe test principles? Hint (Cortisol-competitiveimmunoassay ECLIA, ACTH-sandwich immunoassay) 500 words

Question 7. Provide an example of an abnormal result showing adrenal disease. Describe what actions you would take if you encountered this during validation.200 words

Question 8. Explain sample types required for adrenal function tests and factors which may affect sample integrity. (250 words)

Reference no: EM133897798

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