Effect of arsenate on cells undergoing glycolysis

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Arsenate, AsO43-, acts as a phosphate analog and can replace phosphate in the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) reaction. The product of this reaction is 1-arseno-3-phosphoglycerate. It is unstable and spontaneously hydrolyzes to form 3-phosphoglycerate, as shown below. What is the effect of arsenate on cells undergoing glycolysis?

Reference no: EM13263166

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