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Q. HIV's genome of RNA includes code for reverse transcriptase (RT), an enzyme which acts early in infection to synthesize a DNA genome off of an RNA template. The HIV genome also codes for protease (PR), an enzyme that acts later in infection with cutting long viral polyproteins into smaller, functional proteins. Both RT and PR represent potential targets for antiretroviral drugs. Drugs known as nucleoside analogs (NA) act against RT, whereas drugs called protease inhibitors (PI) act against PR.
Which of these represents the treatment option that is most likely to avoid production of drug-resistant HIV (assuming no drug interactions or side effects)?
a. using a series of NAs, one at a time, and changed about once a week
b. using a single PI, but slowly increasing the dosage over the course of a week
c. using high doses of NA and a PI at the same time for a period not to exceed 1 day
d. using moderate doses of NA and of two different PI's at the same time for numerous months
In the F2 generation, you find that you have 235 flies displaying the wild type phenotype and 765 flies displaying XYZ phenotype. Which phenotype, Wild type or XYZ, is dominant.
The pH of the inner thylakoid space has been measured, as have the pH of the stroma and of the cytosol of a particular plant cell. Which, if any, relationship would you expect to find.
How does this neurotoxin affect the nervous system's ability to stimulate skeletal muscle contraction? How does it affect the capability of skeletal muscle fibers to respond to stimulation.
While hairless hamsters are mated with normal haired hamsters, about one-half the offspring are hairless and one-half are normal. When hairless hamsters are crossed with each other, ratio of normal-haired to hairless is 1:2. How do you account for re..
Why are algae important in nature. Joan and Alex Smith have five daughters who are quite dissimilar in appearance and talents. Examine why this occurs based on the 2 events in meiosis that enhance genetic diversity.
A male rabbit with genotype GgBb. Find out the gametes produced by this rabbit (the sperm would have these combinations of alleles) Hint there are 4 combinations.
Barbara McClintock, famous for discovering that genes might move within genomes, had her meticulous work ignored for nearly 4 decades, but eventually won the Nobel Prize. Why was her work so distrusted.
What techniques might be used to characterize the structure and composition of the structure. Which of the follow will the nurse include in her teaching plan for this patient.
Illustrate the texture and arrangement of the lungs of the cat. If you were asked to create a karyotype from the chromosome spreads you made from HeLa cells, list materials you could use and describe how you would create the karyotype.
Trace the pathway this particle would probably take while moving from outside the cell to inside. What organelles will it pass through? Where will it be located within these organelles.
Modern theory suggests that the early pre-life atmosphere on Earth was a reducing one. Why is it believed that oxygen was not present as life formed on Earth.
A woman from the family with normal cholesterol marries a man with no LDL receptors, and all their children have cholesterol levels twice the normal of the mother.
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