Dogs are extremely susceptible to poisoning by the bromine

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Dogs are extremely susceptible to poisoning by theobromine from chocolate, but only extreme doses complicate humans. Below are the oral LD50s:

                       LD50                                half life

         Dog        300 mg/kg                     17 hr

         Human     1200 mg/kg                  2 hr

Given the data, provide a plausible explanation of why the half-life and LD50 are so different for this toxicant (limit 3-4 sentences)

 

 

Reference no: EM13838747

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