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Assignment
Instructions:
1. Discuss the function in detail of each of the following RNA polymerase II transcription factors.
TFIIB TFIIE TFIIF TFIIH
2. What additional role does one of the subunits of TFIIH have during the initiation phase that involves other protein kinases? What is the end result?
3. Discuss in detail how the 5' cap is formed in eukarytotic mRNAs.
4. What makes the 3' end of eukaryotic mRNAs unique? Describe how this is added.
5. What are the five snRNAs involved in splicing reaction, and describe briefly how they work to assemble spliceosomes.
Sketch image of what you think the histogram of a black and white SPECT image would look like for patient with only fiducial markers, where range of each pixel is [0, 255]
Martha is maintaining her current weight by eating 2,500 kcalories per day. To lose 1 pound of fat per week, she would have to decrease her intake to how several kcalories per day. Considering the albedo of various surfaces how might temperatures var..
Assume that you are responsible for decontamination of materials ina large hospital. how would you decomtaminate (achieve sterility)for each of the following?
Describe a hypothetical metabolic pathway that could explain the inheritance of toenail color in dingbats. The pathway must be consistent with all the data.
Using a specific behaviour as an example, explain thedifference between proximate causes and ultimate causes of behaviour. Explain the important stages in protein digestion, from ingestionthrough excretion of wastes.
Briefly describe the rationale of agents used for bronchodilation in patients with bronchial asthma. What is a mechanism of action of muscarinic antagonists?
Describe the common pattern of alternating extinctions and radiations. Consider Wilson's statement. What evidence can you find to support or refute that statement? Do you agree with Wilson? Explain why you do or don't agree and present the evidenc..
Imagine a population in which an autosomal recessive disease mutation has an allele frequency of 0.04 (q = 0.04).
Track the ingestion and digestion of a ham and cheese sandwich on whole wheat bread with lettuce, green pepper, and tomatoes. Describe the fate of this sandwich from the time you eat it
Biochemical feedback regulation or end product inhibition. What are the most general neurotransmitters in the brain.
Multiple crosses were made between true-breeding lines of black and yellow Labrador retrievers. All F1 progeny were black. When this progeny were inter-crossed, they produced an F2 consisting of 91 black, 39 yellow, and 30 chocolate.
What is the sequence of the non-template strand written in the 5'-3' orientation and What is the sequence of the corresponding region of the mRNA?
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