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So a Toad Cardiac Muscle experiment was conducted and i needed help with these questions
Question 1
Briefly explain the similarities and differences between cardiac muscle and skeletal muscle and smooth muscle?
Question 2
Explain the active length-force relationship in terms of the interactions between actin and myosin molecules in the cardiac muscle?
Question 3
Explain how extracellular calcium concentration affects cytosolic calcium concentration during depolarisation of a cardiac muscle cell?
Question 4
Explain how calcium interacts with the contractile machinery of the cardiac muscle cell to alter contractility?
Question 5
Explain how activation of β-adrenoceptors increases cardiac contractility?
Question 6
What is the mechanism by which nifedipine alters cardiac contractility?
Question 7
What do we mean by the term 'cardiac contractility'? In your answer, consider both the mechanisms at the level of cross-bridge formation and how changes in contractility alter stroke volume in the intact heart?
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